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What is Januvia?
Januvia is an antihyperglycemic drug used for treating diabetes mellitus type 2. Januvia’s official name is Sitagliptin, and it’s produced by the Merck and Co.
pharmaceutical company. It was developed in the early 2000’s and was approved for treatment by the FDA in 2006.
In the time after, Januvia has become a very popular drug in its niche and has even spawned offshoot drugs. Januvia belongs to a class of drugs known as antidiabetics, and works by inhibiting the DPP-4 enzyme.
In turn, this encourages the breakdown of incretins and subsequent increase in the secretion of insulin.
What are the indications for using Januvia?
Januvia is indicated for treating diabetes mellitus type 2. This is a serious metabolic disorder that causes an unhealthy increase in blood sugar .This occurs because type 2 diabetes patients have very little insulin resistance and insulin levels overall.
What is the dosage of Januvia?
Januvia is typically sold as tablets in increments of 25 mg, 50 mg, and 100 mg.
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This medicine should be taken once a day in a dose of 100 mg, though this may vary based on doctors’ recommendations.
Januvia should be kept at room temperature in a dark and dry place, and should be administered orally with or without food and drink.
What are the contraindications for using Januvia?
First of all, Januvia should not be taken by anyone with hypersensitivity issues and an allergy to the drug. Secondly, anyone who suffers from acute pancreatitis, renal impairment and hyperglycemia should not take the drug to avoid negative complications. It should also be noted that some drugs cause interactions when taken with Januvia. These include beta blockers, digoxin, bexarotene, gatifloxacin, and several others. Alcohol use is also known to affect blood glucose levels, so parallel consumption is contraindicated.
What are the adverse effects of Januvia?
Side effects occur in a small percent of patients, and the most common ones include cough, sneezing, ear congestion, sore throat, and body aches, while less common ones may include diarrhea, abdominal pain, headache, dizziness, chills, fever, slurred speech, blurred vision, confusion and nausea.